The durability of road surfaces faces persistent challenges due to increasing traffic loads and the vulnerability of traditional asphalt binders to aging, temperature fluctuations, and fatigue cracking. To address these issues, researchers have explored the integration of nanomaterials into asphalt binders to enhance their durability and rheological performance. Bitumen 60/70 Penetration Grade, commonly produced in Iraq, is rarely used locally due to its sensitivity to temperature variations. In this study, Nano-Copper Oxide was incorporated as a modifier into the asphalt binder at concentrations of 2%, 4%, 6%, and 8% by weight. The modified binders underwent conventional tests such as Penetration, Softening Point, and Ductility, alongside rheological tests including the Dynamic Shear Rheometer and Bending Beam Rheometer. The results revealed significant improvements in penetration reaching about 25% and 37% at 6% content for both unaged and aged samples, respectively. While the lowest temperature susceptibility found at 4% content. Additionally, the viscoelastic behavior was improved, as indicated by higher G* values and lower δ values compared to the original binder with enhanced stiffness and reduced aging effects as confirmed by the Rolling Thin Film Oven Test. Furthermore, the nano-modified binders met SuperPave™ specifications and exhibited resistance to low-temperature cracking only at -6°C and failed at -12°C. These findings suggest the potential for extended pavement service life and increased durability through the use of nano-modified asphalt binders.