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The journal of RESM is open to proposals for special issues on emerging related topics. More info is here.

Research Article

Evaluation of nano sized Mg@BTC metal organic framework as a drug carrier: A long term experimental and predictive theoretical study

Güliz Akyüz1, Aykut Elmas1, Müberra Andaç1,2, Ömer Andaç1,2

1Department of Nanoscience and Nanotechnology, Ondokuz Mayıs University, Samsun, Turkey 2Department of Chemistry, Ondokuz Mayıs University, Samsun, Turkey



Long term release; 

Nano sized Mg@BTC; 

Drug carrier; 

Model fit tests; 

Slow release

Metal Organic Frameworks (MOFs) have found wide applications as a drug carrier in nanotherapeutics because of adjustable pore-sizes, controllable structural properties, large surface area and high pore volume. In this work, nanosized Mg@BTC is synthesized by electrochemical method and used as a new drug carrier for ibuprofen. The ibuprofen (IB) is loaded to the Mg@BTC 1:1 ratio with the amount of %99.8. The release of ibuprofen from nanocarrier has been observed experimentally for long term. After 100.5 hours, the release ratio yields 36 %. The ibuprofen has been tested at 40 ± 0.5 °C. System showed a rapid release after 100 hours, the release ratio yields 72.29 %. The release profile of IB loaded Mg@BTC is tested by using model depended mathematical models to get observation and prediction of the release. Zero Order Model, First Order Model, Higuchi Model, Peppas Model and Hixon Model functions are fitted to the release profiles. Watson’s U Squared Method is used to test the fit strength of the models. Observation from the release profiles, it is seemed Peppas Model yields the best results. Also, thermodynamic analysis has been studied.

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8/12/2023 Special Issue: Embark on a journey of innovation with the journal of Research on Engineering Structures and Materials as we unveil a compelling opportunity for contributors in our upcoming special issue, "Design, Analysis, and Manufacturing of Composite Vehicle Structures." Led by distinguished Guest Editors Liubov Gavva and Oleg Mitrofanov from Moscow Aviation Institute. For more info see the link.

21/10/2023 Journal Submission System Upgrade Completed: We're delighted to announce that our Journal Submission and Tracking System has undergone a significant upgrade, aimed at enhancing your experience. We apologize for the delay, and any inconvenience it may have caused. Here are the key enhancements from a user perspective:

Improvements are designed to make your interaction with our journal smoother and more efficient. Please take the upgraded system for a spin and share your thoughts with us. If you encounter any issues or have questions, please don't hesitate to reach out to our support team.

27/12/2022 Reviewer AwardsThe winners of 2022 reviewer awards of Research on Engineering Structures and Materials (RESM) are announced. More information can be found at Reviewer Awards section. 

(More details of the news may be given in the News section)

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2022 Reviewer Awards:

Please, visit Reviewer Awards section for the winners of the 2022 RESM reviewer awards.

2022 Best Paper Award:

The paper authored by Nitin Kumar, Michele Barbato, Erika L. Rengifo-López and Fabio Matta entitled as “Capabilities and limitations of existing finite element simplified micro-modeling techniques for unreinforced masonry” is awarded the 

2022 Most Cited Paper Award:

The paper authored by Aykut Elmas, Güliz Akyüz, Ayhan Bergal, Müberra Andaç and Ömer Andaç entitled as “Mathematical modelling of drug release" is awarded the


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