RESM

   

Submission & tracking

For submitting new manuscripts or tracking the existing ones, login or register to the Submission Tracking System.


LOGIN / REGISTER

Special issue

Special Issue Proposals:

The journal of RESM is open to proposals for special issues on emerging related topics. More info is here.

LATEST events

PARTNERS




Research Article

Fabrication and in-vitro evaluation of copper doped bioactive glass/polymer composite scaffolds for bone tissue engineering

Ahsen Ünal, Işıl Özer, Melek Erol Taygun, Sadriye Küçükbayrak

Department of Chemical Engineering, Chemical and Metallurgical Engineering Faculty, Istanbul Technical University, Turkey                                                                                                                       

Keywords

Abstract




Composite; 

Scaffold;    

Bioactive glass; 

Therapeutic ion;

Bone tissue engineering


Composites developed by combining bioactive glasses and biopolymers are attractive materials for use in bone tissue engineering scaffolds due to their bioactivity, biocompatibility, osteoconductivity and mechanical properties. From this point of view, in this study, three-dimensional polymer/bioactive composite scaffolds were fabricated by using polymer foam replication method. To be able to achieve this goal, in the first stage new bioactive glass composition in the system SiO2-CaO-Na2O-P2O5 were developed with the incorporation of copper which have antibacterial and angiogenic properties. Scaffolds that mimic the structure of the foams were obtained after the heat treatment process. Then, the scaffolds were coated with gelatine at different percentages (1 and 3 weight%) in order to improve mechanical properties of the scaffolds. Microstructural, physical, chemical and mechanical properties of the composite scaffolds were investigated by using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction analysis (XRD), compressive strength test and porosity measurements. Furthermore, bioactivity and biodegradability behavior of the samples were determined by in vitro simulated body fluid (SBF) studies. The results showed that all scaffolds favored precipitation of calcium phosphate layer when they were soaked in SBF; they can also deliver controlled doses of copper toward the SBF medium. It was concluded that scaffolds coated with gelatine may be promising candidates for bone tissue engineering applications due to their porosity, bioactivity and appropriate biodegradation rate.

© 2019 MIM Research Group. All rights reserved.

LATEST News


27/12/2022 Reviewer Awards: The winners of 2022 reviewer awards of Research on Engineering Structures and Materials (RESM) are announced. More information can be found at Reviewer Awards section. 


23/12/2022 Best Paper Award: According to the Advisory Board decision, the paper authored by Nitin Kumar, Michele Barbato, Erika L. Rengifo-López and Fabio Matta entitled as “Capabilities and limitations of existing finite element simplified micro-modeling techniques for unreinforced masonry” is awarded the 2022 Best Paper Award of Research on Engineering Structures and Materials (RESM). 

23/12/2022 Most Cited Paper Award:  According to the Editorial Board evaluation, the paper authored by Aykut Elmas, Güliz Akyüz, Ayhan Bergal, Müberra Andaç and Ömer Andaç entitled as “Mathematical modelling of drug release" is awarded the 2022 Most Cited Paper Award of Research on Engineering Structures and Materials (RESM). 


13/04/2022 Fraudulent Emails Impersonating Our Journal: We noticed that some emails are sent to some people impersonating our journal staff as sender and requesting recipients to follow some links. Our journal and staff has nothing to do with these emails and please do not follow the given links. Senders seem to have malicious aims. The emails include a portion of some of our previous emails to the journal users and researchers. This is only to deceive the receiver and make them trust the email. Do not follow any links or perform suspicious actions specified in these emails. Please, check the sender info carefully. Even the sender address or name resembles the journal related words they are different, generally in an easily noticeable way.


(More details of the news may be given in the News section)


For more see News...

LATEST AWARDS


2022 Reviewer Awards:

Please, visit Reviewer Awards section for the winners of the 2022 RESM reviewer awards.


2022 Best Paper Award:

The paper authored by Nitin Kumar, Michele Barbato, Erika L. Rengifo-López and Fabio Matta entitled as “Capabilities and limitations of existing finite element simplified micro-modeling techniques for unreinforced masonry” is awarded the 


2022 Most Cited Paper Award:

The paper authored by Aykut Elmas, Güliz Akyüz, Ayhan Bergal, Müberra Andaç and Ömer Andaç entitled as “Mathematical modelling of drug release" is awarded the


abstractıng/ındexıng

  • Asos Indeks
  • CiteFactor
  • Cosmos
  • CrossRef
  • Directory of Research Journal Indexing
  • Engineering Journals (ProQuest)
  • EZB Electronic Journal Library
  • Global Impact Factor
  • Google Scholar
  • InfoBase Index
  • International Institute of Organized Research (I2OR)
  • International Scientific Indexing (ISI)
  • Materials Science & Engineering Database (ProQuest)
  • Open Academic Journals Index
  • Publication Forum
  • Research BibleScientific Indexing Service
  • Root Indexing
  • Scopus
  • Ulakbim TR Index (Tubitak)
  • Universal Impact Factor
  • Scope Database




MIM RESEARCH GROUP

©2014. All rights reserved

Contact :

jresm@jresm.net

editor.jresm@gmail.com


Postal Address:

Kemal Öz Mah. 3. Bilgi Sok., 4A, No:13 Usak/Turkey



Last Update:

02.02.2023

(dd.mm.yyyy)